JimJimJimJim Posted April 28, 2014 Share Posted April 28, 2014 Jim Marshall (not a doctor) said ... The ENZAMET trial is one of the two clinical trials of the drug Enzalutamide that have now begun in Australia. The ENZAMET trial is for men who have metastatic prostate cancer. Men in the trial will have standard hormone therapy - an LHRH agonist such as Zoladex plus an non-steroidal anti-androgen. Half the men will use one of the current non-steroidal anti-androgens (bicalutamide, nilutamide or flutamide). The other half will use the new non-steroidal anti-androgen Enzalutamide. You cannot enter this trial if you have had your prostate cancer treated by: hormone treatment longer than 2 years. There are more detailed rules of how you may or may not qualify available from the trial site: https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365575 The hospitals offering this trial are: Northern Cancer Institute - Frenchs Forest - Frenchs Forest Royal Prince Alfred Hospital - Camperdown Prince of Wales Hospital - Randwick Concord Private Hospital - Concord St Vincent's Hospital (Darlinghurst) - Darlinghurst Wollongong Hospital - Wollongong St George Hospital - Kogarah Sydney Adventist Hospital - Wahroonga Nepean Hospital - Kingswood Port Macquarie Base Hospital - Port Macquarie Peter MacCallum Cancer Institute - East Melbourne St Vincent's Hospital (Melbourne) Ltd - Fitzroy Epworth Eastern Hospital - Box Hill Austin Health - Austin Hospital - Heidelberg Peninsula Oncology Centre - Frankston Royal Brisbane & Womens Hospital - Herston Princess Alexandra Hospital - Woolloongabba Nambour General Hospital - Nambour Gold Coast Hospital - Southport The Royal Adelaide Hospital - Adelaide Flinders Medical Centre - Bedford Park Royal Perth Hospital - Perth Royal Hobart Hospital - Hobart Royal Darwin Hospital - Tiwi Non-steroidal anti-androgens include: Cosudex/Casodex (bicalutamide), Anandron/ Nilandron (Nilutamide), Eulexin (Flutamide), Enzalutamide. Androcur (Cyproterone), is a steroidal anti-androgen) PCFA also has an excellent description of this trial at: http://www.prostate.org.au/articleLive/pages/Australian-Organisation-Launches-Large-International-Clinical-Trials-in-Prostate-Cancer.html ... end Jim Link to comment Share on other sites More sharing options...
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