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Enzalutamide trial in Australia for high-risk prostate cancer as yet untreated


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Jim Marshall (not a doctor) said ...

The ENZARAD trial is one of the two clinical trials of the drug Enzalutamide that have now begun in Australia.


The ENZARAD trial is essentially for those who have high-risk prostate cancer but have had almost no treatment yet. 


Men in the trial will have standard radiation (external beam radiotherapy). Half the men will follow this by standard hormone therapy. The other half will use enzalutamide as their hormone therapy.


You cannot enter this trial if you have had your prostate cancer treated by: 

  • surgery;
  • radiation; or 
  • hormone treatment longer than 30 days.


You have to be at high risk to enter the trial. 

Your biopsy score (Gleason score) must be:

  • 8, 9 or 10; OR
  • 7 (4+3) together with a PSA of 20 or more, OR
  • 7(4+3), cancer in both sides of the prostate and a PSA of 10 or more.


There are more detailed rules of how you may or may not qualify available from the trial site:



The hospitals offering this trial are:

Westmead Hospital - Westmead

Prince of Wales Private Hospital - Randwick

Wollongong Hospital - Wollongong

Calvary Mater Newcastle - Waratah

Peter MacCallum Cancer Institute - East Melbourne

Box Hill Hospital - Box Hill

Austin Health - Austin Hospital - Heidelberg

Royal Brisbane & Womens Hospital - Herston

Princess Alexandra Hospital - Woolloongabba

Mater Adult Hospital - South Brisbane

Nambour General Hospital - Nambour

Flinders Medical Centre - Bedford Park

Repatriation Hospital - Daw Park

Royal Perth Hospital - Perth

Fremantle Hospital and Health Service - Fremantle

Royal Hobart Hospital - Hobart


PCFA also has an excellent description of this trial at:



... end Jim

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