Paul Edwards Posted February 16, 2014 Share Posted February 16, 2014 A retrospective study (The Prognostic Importance of Metastatic Site in Men with Metastatic Castration-resistant Prostate Cancer) has been published in the journal European Urology. The study examined data collected in the TAX 327 phase 3 trial to investigate the impact of the site of metastasis on overall survival (OS). The study found that the pattern of spread confers a differential prognostic impact in men with metastatic castration-resistant prostate cancer: Men with liver metastases with or without other metastases had the shortest median OS in the study; men with lung metastases with or without other metastases had 2nd shortest median OS in the study; men with bone-plus-node disease came next in terms of median OS then, men with bone-only metastases; and men with lymph node-only disease had the best median OS in the study. The authors indicated that their findings needed to be validated against further data. Link to comment Share on other sites More sharing options...
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