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Fish and fish oils - deep frying increases prostate cancer risk, especially advanced prostate cancer


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Jim Marshall (not a doctor) said ...

This study showed that all deep fried foods (except potato crisps) studied increased your prostate cancer risk.


Deep fried fish more than once a week increased your prostate cancer risk by 32%, and your risk of advanced prostate cancer by 41%.

... end Jim

Prostate. 2013 Jun;73(9):960-9. doi: 10.1002/pros.22643. Epub 2013 Jan 17.

Consumption of deep-fried foods and risk of prostate cancer.

Stott-Miller M, Neuhouser ML, Stanford JL.


Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA.



Evidence suggests that high-heat cooking methods may increase the risk of prostate cancer (PCa). The addition of oil/fat, as in deep-frying, may be of particular concern, and has not specifically been investigated in relation to PCa. Potential mechanisms include the formation of potentially carcinogenic agents such as aldehydes, acrolein, heterocyclic amines, polycyclic aromatic hydrocarbons, and acrylamide.


We estimated odds ratios (OR) and 95% confidence intervals (CI) for the association between tertiles of intake of deep-fried foods from a food frequency questionnaire (French fries, fried chicken, fried fish, doughnuts and snack chips) and PCa risk, adjusted for potential confounders, among 1,549 cases and 1,492 controls. We additionally examined associations with more aggressive PCa (defined as regional/distant stage, elevated Gleason score or prostate-specific antigen level).


Compared with <1/week, there was a positive association with PCa risk for intake ≥1/week of French fries (OR = 1.37; 95% CI, 1.11-1.69), fried chicken (OR = 1.30; 95% CI, 1.04-1.62), fried fish (OR = 1.32; [jm: a 32% greater risk of prostate cancer] 95% CI, 1.05-1.66), and doughnuts (OR = 1.35; 95% CI, 1.11-1.66). There was no association for snack chips (OR = 1.08; 95% CI, 0.89-1.32). Most of the estimates were slightly stronger for more aggressive disease (OR = 1.41 ; [jm: a 41% greater risk of aggressive prostate cancer] 95% CI, 1.04-1.92 for fried fish).


Regular consumption of select deep-fried foods is associated with increased PCa risk. Whether this risk is specific to deep-fried foods, or whether it represents risk associated with regular intake of foods exposed to high heat and/or other aspects of the Western lifestyle, such as fast food consumption, remains to be determined.

Copyright © 2013 Wiley Periodicals, Inc.

PMID: 23335051


This extract can be found on http://PubMed.com, and is in the public domain.

On PubMed.com there will be a link to the full paper (often $30, sometimes free).


Any highlighting (except the title) is not by the author, but by Jim Marshall.

Jim is not a doctor.

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