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Ask Dr. Snuffy Myers video: Zytiga vs Ketoconazole


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Notes from Ask Dr. Myers video:

Zytiga vs Ketoconazole

  • Zytiga alternative to Carbazitaxel after chemotherapy failure
  • Zytiga on empty stomach! 4 pills at once per day
  • Blocks adrenal gland so take prednisone (or retain salt and hence hypertension)
  • Can tip heart problem over the edge
  • Both share drug interaction problem with grapefruit juice
  • Cough remedies especially dangerous.
  • Both cause liver damage.
  • So drugs much the same except Zytiga proven after chemotherapy.
  • Snuffy Myers says Ketoconazole works after chemo, but not proven.
  • So Zytiga is just as complex as Ketoconazole.
  • Myth - Ketoconazole works by lowering testosterone.
  • Ketoconazole will destroy prostate cancer cells that do not respond to testosterone.
  • Dr Snuffy Myers says often has Ketoconazole response with measured high levels of testosterone.
  • Different drugs - different targets.
  • Snuffy Myers has seen response to Ketoconazole after Zytiga failure, and expects the reverse to be true.
  • So drugs complimentary rather than competitive.

Search Google for

zytiga dr myers video

and view the original yourself.

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