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Radium-223 Therapy for Bone Metastases a 12 min video


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Considerations relating to  Radium-223 Therapy.


I found this to be worthwhile for anyone with advanced metastatic disease predominately in the bones that may wish to discuss this treatment with their oncologist. Please note: The possible combination treatment with Abiraterone has been discontinued as it is now considered to be dangerous (see post on this site). However the rest of the presentation is informative and up to date.

For a simpler more understandable version of Radium-223 Therapy check out our own JimJImJimJIm version on this site.Just go to the top bar and click on:-  Our You Tube videos.

This video is an excerpt from Dr. Eric Rohren's state of the art presentation on Radium-223.  This discussion includes the operationalization of Radium-223 at MD Anderson. In addition treatment it contains a review of the different agents available for imaging skeletal metastases in patients with metastatic castration-resistant prostate cancer.

It also takes a look at patient prognosis and survival data.

This video is on the Uro Today site and it is intended for a professional audience. To go to this video just click on this link https://tinyurl.com/ybe9augt

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On ‎1‎/‎26‎/‎2018 at 11:09 AM, Barree said:

I found this to be worthwhile for anyone with advanced metastatic

Is Radium 223 available in Oz yet?

The video at https://tinyurl.com/ybe9augt was interesting, and the images of men's skeletons with extensive bone cancer was beyond sobering, more like very frightening. And the Ra223 just didn't seem to work in all cases where tumors partially reduced in some areas but then were seen in other areas within a few months.

Today, I listened to Robyn Williams and a gang of scientists on Science Show talking about Quantum computing, where problems which might take 3,000 years to solve on your lap top could be solved in minutes with a quantum computer. Ah yes, a whole lot more GeeWizery lies ahead, so could it be used to find a more effective drug for Pca? "Maybe" seems to be the answer to all such questions, 

and what about WHEN? Oops, The Science Show does not do "whens".  Many years later than we might hope it seems. Too late for me, and many others.

I had a "small amount" of bone mets last June, so would it not be good to get a hit with Ra223 asap? This kinda question wasn't answered in video where it seemed that Ra223 is used on patients with huge tumor load, and who look like they may only have months to live if nothing is done, and the Docetaxel is doing much to alter that. I often think it'd be better to hit Pca early rather than later, but it seems the medical system likes to stretch out the treatments which all eventually fail, and the conspirisists have a field day when they say "Look how they delay the treatments to allow the medics to make huge piles of money along the way...." 


Where is the link to post about danger of abiraterone with Ra223?  


Try to keep well everyone. I have found it very difficult, no matter what I try.  Aunty Destinee is a difficult person to deal with.

Patrick Turner. 

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Hi Patrick,

To find the info you are looking for enter this:- Researchers halt study early on Bayer’sXofigo combo study.     into the search bar on the top of our site. I notice that Nev has provided the link to full article - this contains what you are looking for.


Xofigo (Radium223) has been approved for use in Australia but I don't think the necessary legislation has been put through yet to permit it to be prescribed under PBS/Medicare- but it shouldn't be long.

Recurrence after treatment for Prostate Cancer is  not unusual - no mater what treatment is used - - everyone's metabolism is different and we all respond differently to the various Cancer treatments that are prescribed.

Treatments such as Radium 223 are in their infancy and oncologist are still in the process of trying to work out how to best utilize and administer these treatments to obtain the best effect.

The important thing is, in Australia we are lucky enough to have these new treatments coming up all the time -some will work and some wont.

The use of all new treatments is strictly controlled by the Government and there is a plethora of regulations governing the use radio active isomers fix brokenbut we are extremely fortunate in that these advanced treatments are progressively being made available to us - thanks to lobby groups such as this one JImJImJImJim and the members of the group  who put so much effort into getting Radium223 approved.



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21 hours ago, Barree said:

To find the info you are looking

........is not so easy. I could not find just why Ra223 and Zytiga should not be used together, but I see talk of talk of increased bone fractures. It kinds of stands to reason. The cancer goes to bones, which then  become weaker, like chalk, and the Ra22 is added, and maybe cancer is killed, but what is left behind? do the bones somehow remake themselves to be restored to how they were ?

So say you buy the expensive Ra223, and get lucky, and cancer "goes away". But what are you left with? do the side effects of both cancer and its treatment leave you frightened to cough lest your ribs break, frightened to walk, let alone do some gardening or go for a ride on a bike.

The recurrence of cancer after treatment is often not something re-occurring after it had been stopped. The word "recurrence" irritates me. The cancer wasn't stopped when first treated, ok, and doctors failed, OK, and cancer continued on because doctors could not remove all PG cells at RP site, and nobody could see the hundreds of microscopic mets all over your body at time of RP. 

And not all respond to ADT, and all ADT fails because cancer mutates so it does not need testosterone, or the dihydro-testosterone. I know a guy who has taken only 2.5 years from diagnosis to chemo after RP, RT and ADT all failed so fast he found it difficult to accept.


There are blokes whose tiny amount of initial tumour in PG makes a large amount of Psa and they get treated before Pca spreads. In many cases, they never have to worry again, and can accept the sexual mutilation and maybe incontinence. But where a man has low Psa produced by his PG tumour, it grows to a Gleason 9 monster before its detected, and it has already spread all over the body, and then there is no cure, like my oncologist said, and its just a battle against time, and it can be expensive, and just how much time is gained, and is it worth the dough and loss of QOL? 


I think convincing the Govt to fund Ra223 is a noble ambition. But we ought to be telling the Govt to lower the threshold of Psa from 5 to 2.5 for funded examination of PG. Many more examinations would be done, and costs would increase, but methinks less would have to be spent on later treatments that are trying to catch the horse after it bolted. Prevention should cheaper than attempted cures which give limited time. By the time you get to see a specialist urologist and get a biopsy, or MRI, the Psa that was 2.5 may have moved to 3.0.

Blokes whose father and brothers had Pca should be allowed to have PG cut out BEFORE any cancer appears, a pre-emptive strike, and with the right surgeon all nerves can be spared, and the bloke pisses well and enjoys his sexuality. This would avoid the widespread depression that follows Pca treatments with ADT and RT etc. Men also need to know if they have DNA likely to give Pca, methinks men whose sisters get Bca and Oa are sitting ducks for Pca.  

Patrick Turner. 

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