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Early chemo, PSA fall, Bone advance


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J La State Med Soc. 2008 Mar-Apr;160(2):99-100.

Prostate specific antigen (PSA) may be a poor marker for progression of prostate cancer after treatment with a combination of chemo-hormonal therapies.

Sartor O.


Stanley Scott Cancer Center, New Orleans, Louisiana, USA.


Prostate specific antigen (PSA) is typically the first indicator of relapse in patients treated for prostate cancer. Though radiographic progression with an undetectable PSA is clearly documented in the literature, this is an unusual event. We describe two cases of patients treated with a combination of androgen deprivation and chemotherapy for early stage but high risk prostate cancer who manifested clear evidence of radiographic relapse despite PSA values of <0.1 ng/mL. We hypothesize that patients with early stage prostate cancer treated with combinations of androgen deprivation and chemotherapy may be at high risk for this unusual pattern of relapse.

PMID: 18681353 Forum: Metastatic prostate cancer Title: Early chemo, PSA fall, Bone advance

This extract can be found on http://PubMed.com, and is in the public domain.

On PubMed.com there will be a link to the full paper (often $30, sometimes free).

Any highlighting (except the title) is not by the author, but by Jim Marshall.

Jim is not a doctor.

This page was found on the Advanced Prostate Cancer Community for Australian men at http://advancedprost...lia.ipbhost.com.

The link is hard to remember.

An easier way to find it is to go to JimJimJimJim.com and click on Prostate.

That's the word Jim four times, no spaces, followed by .com.

If you need other help - to perhaps find someone to talk to or a local support group:

Click on the Contact Jim button at http://JimJimJimJim.com.

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