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Snuffy says grape seed extract long term unknown but ...

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Grape seed extract [jm] regulates androgen receptor-mediated transcription in prostate cancer cells through potent anti-histone acetyltransferase activity - Abstract

Wednesday, 23 February 2011

Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.

Histone acetylation, which is regulated by histone acetyltransferases (HATs) and deacetylases, is an epigenetic mechanism that influences eukaryotic transcription. Significant changes in histone acetylation are associated with cancer; therefore, manipulating the acetylation status of key gene targets is likely crucial for effective cancer therapy. Grape seed extract (GSE) has a known protective effect against prostate cancer. Here, we showed that GSE significantly inhibited HAT activity by 30-80% in vitro (P?

Written by:

Park SY, Lee YH, Choi KC, Seong AR, Choi HK, Lee OH, Hwang HJ, Yoon HG.

Reference: J Med Food. 2011 Jan-Feb;14(1-2):9-16.

doi: 10.1089/jmf.2010.1264

PubMed Abstract

PMID: 21244239 Forum: Other prostate cancer topics including radiation Title: Snuffy says grape seed extract long term unknown but ...

This extract can be found on http://PubMed.com, and is in the public domain.

On PubMed.com there will be a link to the full paper (often $30, sometimes free).

Any highlighting (except the title) is not by the author, but by Jim Marshall.

Jim is not a doctor.

This page was found on the Advanced Prostate Cancer Community for Australian men at http://advancedprost...lia.ipbhost.com.

The link is hard to remember.

An easier way to find it is to go to JimJimJimJim.com and click on Prostate.

That's the word Jim four times, no spaces, followed by .com.

If you need other help - to perhaps find someone to talk to or a local support group:

Click on the Contact Jim button at http://JimJimJimJim.com.

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