ADT may wake u at night with flashes & need to pee Reference

[JimmyToowong]

Sleep and daily functioning during androgen deprivation therapy for prostate cancer

Department of Psychiatry, School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

A limited body of evidence suggests that sleep problems are common in prostate cancer patients undergoing androgen deprivation therapy, yet little is known about sleep characteristics and the effects of poor sleep on daily functioning in this population. This study assessed sleep in 60 prostate cancer patients taking androgen deprivation therapy with wrist actigraphy and daily diaries for 7 days. The Epworth Sleepiness Scale and the general version of the Functional Assessment of Cancer Therapy scale were also administered. On average, total sleep time was 5.9 (SD = 1.4) h, and sleep efficiency was 75% (SD = 12.0) as assessed by actigraphy. There was generally poor concordance between actigraphy and daily diary for most sleep metrics. Subjects reported awakening, on average, 2.7 times per night, most commonly for nocturia and hot flashes. Assessment of daily functioning showed that participants had mild daytime sleepiness, which was predicted by total sleep time (F(1,47) = 4.5, P= 0.04) General quality of life was not impaired. This study supports more research on the predictors of poor sleep in order to identify effective interventions.

Written by:

Hanisch LJ, Gooneratne NS, Soin K, Gehrman PR, Vaughn DJ, Coyne JC. [1]

Reference: Eur J Cancer Care (Engl). 2010 Sep 6. Epub ahead of print.

PMID: 20825464 Forum: Primary hormone therapy Title: ADT may wake you at night with hot flashes and need to pee

References

This extract can be found on http://PubMed.com, and is in the public domain.

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