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PSA flare with Zytiga (abiraterone) does not affect results if PSA falls significantly


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Jim Marshall (not a doctor) said ...

An earlier article told us that even if Jetvana (Cabazitaxel) caused the PSA to rise at first (flare), if it then dropped a lot the flare did not make a difference.





The same is true for flare in Zytiga (abiraterone). 


... end Jim



In a retrospective study, we analyzed the PSA flare after abiraterone treatment in patients with castration-resistant prostate cancer (CRPC) and correlated it with prostate-specific antigen (PSA) declines and clinical outcome. Early PSA flare occurred in 9 of 103 (8.7%) cases. There were no substantial differences in the clinical outcomes between patients who experienced the PSA flare and those who had an immediate PSA response.

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