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Enzalutamide trial in Australia for high-risk prostate cancer as yet untreated


JimJimJimJim

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Jim Marshall (not a doctor) said ...


The ENZARAD trial is one of the two clinical trials of the drug Enzalutamide that have now begun in Australia.


 


The ENZARAD trial is essentially for those who have high-risk prostate cancer but have had almost no treatment yet. 


 


Men in the trial will have standard radiation (external beam radiotherapy). Half the men will follow this by standard hormone therapy. The other half will use enzalutamide as their hormone therapy.


 


You cannot enter this trial if you have had your prostate cancer treated by: 


  • surgery;
  • radiation; or 
  • hormone treatment longer than 30 days.

 


You have to be at high risk to enter the trial. 


Your biopsy score (Gleason score) must be:


  • 8, 9 or 10; OR
  • 7 (4+3) together with a PSA of 20 or more, OR
  • 7(4+3), cancer in both sides of the prostate and a PSA of 10 or more.

 


There are more detailed rules of how you may or may not qualify available from the trial site:


https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=365611


 


The hospitals offering this trial are:


Westmead Hospital - Westmead


Prince of Wales Private Hospital - Randwick


Wollongong Hospital - Wollongong


Calvary Mater Newcastle - Waratah


Peter MacCallum Cancer Institute - East Melbourne


Box Hill Hospital - Box Hill


Austin Health - Austin Hospital - Heidelberg


Royal Brisbane & Womens Hospital - Herston


Princess Alexandra Hospital - Woolloongabba


Mater Adult Hospital - South Brisbane


Nambour General Hospital - Nambour


Flinders Medical Centre - Bedford Park


Repatriation Hospital - Daw Park


Royal Perth Hospital - Perth


Fremantle Hospital and Health Service - Fremantle


Royal Hobart Hospital - Hobart


 


PCFA also has an excellent description of this trial at:


http://www.prostate.org.au/articleLive/pages/Australian-Organisation-Launches-Large-International-Clinical-Trials-in-Prostate-Cancer.html


 


... end Jim


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